Analytical Chemistry Scientist II

JOB TITLE: Analytical Chemistry Scientist II

LOCATION: San Diego, CA – Onsite

SCHEDULE: 8:00 AM – 5:00 PM

DURATION: 12-month contract

PAY: 40-45 USD per hour

Job Responsibilities:

In this role, you will support analytical method development, validation, and transfer within a fast-paced biopharmaceutical environment focused on oligonucleotide synthesis and testing. Key responsibilities include:

• Developing, optimizing, validating, and transferring analytical methods for oligonucleotides, raw materials, and reagent consumables
  
• Designing, planning, and executing laboratory experiments with minimal supervision
  
• Managing multiple assignments and delivering high-quality results within project timelines
  
• Performing data analysis, interpreting results, and troubleshooting analytical issues
  
• Preparing study protocols, technical reports, and assay work instructions with high attention to detail
  
• Ensuring compliance with GMP, Good Documentation Practices (GDP), and internal quality standards
  
• Supporting cross-functional collaboration and continuous improvement initiatives
  
• Performing additional duties as assigned by management
  
  

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  Essential Duties and Job Functions:

• Execute and support analytical method development, qualification, validation, and transfer activities
  
• Perform hands-on laboratory work using chromatographic and spectroscopic techniques
  
• Conduct oligonucleotide characterization and release testing
  
• Ensure accurate documentation and adherence to regulated laboratory practices
  
• Investigate and resolve unexpected analytical results using scientific problem-solving approaches
  
• Collaborate with cross-functional teams to support method lifecycle activities
  
• Contribute to assay development, optimization, and standardization efforts
  
• Maintain compliance with FDA cGMP, ICH guidelines, USP requirements, and internal quality systems
  
• Support continuous improvement initiatives within analytical development workflows
  
  

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  Knowledge & Skills:

• Strong hands-on laboratory skills with excellent organization and documentation practices
  
• Proficiency in analytical techniques including HPLC, LC-MS, UV-Vis, FTIR, Karl Fischer, and NMR
  
• Experience with oligonucleotide analysis and characterization
  
• Strong understanding of method development, validation principles, and regulatory expectations (FDA, ICH, USP)
  
• Excellent problem-solving, analytical thinking, and troubleshooting abilities
  
• Ability to manage multiple priorities in a fast-paced, deadline-driven environment
  
• Strong communication skills (verbal and written) and ability to collaborate across teams
  
• Familiarity with GMP environments and quality systems
  
• High attention to detail and commitment to data integrity
  
• Ability to work independently while contributing effectively in a team setting
  
  

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  Education & Experience:

• Bachelor’s, Master’s, or Ph.D. in Analytical Chemistry, Chemistry, Biochemistry, Molecular Biology, or related scientific field
  
• Minimum 2 years of hands-on experience in analytical method development, validation, qualification, and transfer
  
• Direct experience with oligonucleotide analytical testing strongly preferred
  
• Experience working in GMP-regulated or pharmaceutical/biotech environments preferred
  
• Strong academic or industry background in chromatographic and spectroscopic methods required
  

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